Quantifying unique sources of value

Many healthcare innovations provide value beyond what traditional measures of cost-effectiveness capture. PHE is a leader in measuring unique components of the value of health technologies and communicating this value to stakeholders.

This research on the value of innovation has been instrumental in shaping policymaker and payer opinions on the benefits of treatments for cancer, HIV, cardiovascular disease, and other diseases. PHE work on quantifying novel components of value has been published in leading health policy outlets such as Health Affairs, Harvard Business Review, and the American Journal of Managed Care.

Experts at PHE have developed and refined value concepts in the healthcare setting, including the following:

  • Social value includes the economic value of medical innovations’ health, productivity, and cost impacts to generate a comprehensive estimate of the value an innovation provides to society overall.
  • Insurance value captures the value healthy individuals place on protection from or treatment for a disease that they may develop in the future. For example, access to a treatment for cancer provides value to healthy individuals similar to an insurance plan. By knowing they can receive treatment, healthy individuals benefit even if they never ultimately get the disease.
  • Option value represents the value that a medical innovation provides by preserving life and functional status, giving patients the option to benefit from future innovations or even cures. In disease areas with rapid drug innovation like cancer, the benefits of extending survival by 1 year are compounded by the introduction of new therapies that further extend life.
  • Value of hope is a novel component of value stemming from research conducted by PHE on patient preferences for long-term survival. Value of hope reflects the finding that some patients may place greater value on treatments with a small chance of long-term survival over treatments that offer a similar, but certain, average survival outcome.

This research on the value of cancer care has been published in multiple special issues of the journals Health Affairs and the American Journal of Managed Care.

PHE’s approach to quantifying value is customized to each situation and may involve use of any of our methodological capabilities for analysis and communication.


Precision Medicine Group is an integrated team of experts in fields from advanced lab sciences to translational informatics and regulatory affairs, payer insights to marketing communications. Together, we help our pharmaceutical and life-sciences clients conquer product development and commercialization challenges in a rapidly evolving environment.